Reeve is probably best known for his role as Superman and an accident which left him paralyzed from the neck down.
Reeve was in Minneapolis October 27, 1996 speaking at the Courage Center, a support organization for the disabled. According to David Peterson's story in the October 29 Minneapolis Star-Tribune, the following exchange took place:
Q: Do you believe in the Lord?
A: Even though I don't personally believe in the Lord, I try to behave as though He was watching.
Peterson writes the audience responded with "Huge applause for a moment that was typical for its simplicity and candor."